1874, East Texas. Two friends pursue the Posse, a group of sadistic human traffickers who have kidnapped five women. Along with an Indian scout, they race against time to find and free the women before the traffickers sell them to sex-slave buyers at the Mexican border.

An innocent young man, Jack, goes on an epic quest to rescue his sister Lula after she has been kidnapped by the violent killer Cut Throat Bill and her gang. To save her, Jack enlists the help of a crafty bounty hunter named Reginald Jones, a grave-digging alcoholic son of an ex-slave, and a street-smart prostitute. The gang tracks Cut Throat Bill into the deadly no-man’s land known as The Big Thicket — a place where blood and chaos reign.

Um homem da lei da fronteira faz parceria com um detetive indiano para caçar um bando implacável de criminosos adolescentes conhecido como Rufus Buck Gang.